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Op. Dr. Sunay Cafer

Non-surgical

Botulinum Toxin

Botulinum toxin softens the lines made by facial muscle movement. Which areas it treats, how long it lasts, what it cannot do, and its risks.

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What is botulinum toxin treatment?

Botulinum toxin is a purified protein that temporarily reduces the signal from nerve to muscle. Injected in small, measured doses into specific facial muscles, it softens the movement that creates certain lines.

The important word is temporary. The effect builds over about two weeks, holds for a few months, and then fades as nerve signalling recovers. Nothing is removed and nothing is permanently altered.

It is a medical treatment, given by a physician, using a prescription product — not a cosmetic in the everyday sense.

Which areas can be treated?

AreaWhat it addresses
Glabella (between the brows)The vertical "frown" lines
ForeheadHorizontal lines from raising the brows
Crow's feetLines fanning from the outer corners of the eyes
Bunny linesCreases across the upper nose on scrunching
Brow positionA slight lift of the outer brow, by relaxing the muscles that pull it down
ChinDimpling or "orange peel" texture of the chin
Masseter (jaw muscle)Reducing bulk in an overdeveloped chewing muscle
Gummy smileExcessive upper lip elevation on smiling

Not all of these suit every face, and some — brow position, gummy smile, masseter — depend heavily on accurate assessment of how your own muscles work. That assessment happens before any injection.

What it does not treat

This is worth stating plainly, because it is the most common source of disappointment:

  • Static lines — creases visible when the face is completely at rest — respond partially at best. They are a skin problem, not only a muscle problem.
  • Volume loss in the cheeks, temples or around the mouth is not treated by relaxing muscle; that is what fillers address.
  • Loose skin and jowls are not lifted by botulinum toxin. Beyond a certain point, only surgery changes them.
  • Sun damage, pigmentation and skin texture are unaffected.

A consultation that promises botulinum toxin as an answer to all of the above is not being straight with you.

What does the evidence show?

Botulinum toxin for facial expression lines is among the most studied treatments in aesthetic medicine. A systematic review and meta-analysis by Rahman and colleagues examined efficacy and duration in upper facial expression lines with dose optimisation, published in the Aesthetic Surgery Journal in 2023.

The consistent findings across this literature are that it works for dynamic lines, that the effect is temporary, and that duration varies with dose and with the individual. That is the whole honest summary.

How is the treatment performed?

  1. Assessment. Your face is examined at rest and in movement — frowning, raising the brows, smiling. Muscle strength and asymmetry are noted. Medical history and medications are reviewed.
  2. Planning. Injection points and doses are marked according to how your muscles actually behave, not to a standard template.
  3. Injection. Very fine needles; the appointment usually takes fifteen to thirty minutes. Anaesthesia is not normally needed.
  4. Aftercare. Stay upright for several hours, do not rub the area, and postpone strenuous exercise and saunas until the next day.
  5. Review at two weeks. The effect is fully developed by then. Any small adjustment is made at this appointment.

What happens afterwards?

PeriodWhat is usual
ImmediatelySmall raised bumps at injection points, settling within an hour; occasional pinpoint bruising
Days 1–2No visible change yet; normal activity
Days 3–7Movement begins to soften
Week 2Full effect; review appointment
Months 2–3Effect stable
Months 3–4Movement gradually returns

There is no downtime. Most people are treated and go straight back to work.

What are the risks?

  • Bruising or swelling at injection sites, usually minor and short-lived.
  • Headache in the first day or two.
  • Drooping of the upper eyelid (ptosis) or of an eyebrow — uncommon, caused by spread to a neighbouring muscle. It is temporary but can last several weeks.
  • Asymmetry, usually correctable at the two-week review.
  • An unnatural or over-treated appearance where the dose is too high — an argument for starting conservatively.
  • Dry eye or altered smile, depending on the area treated.
  • Allergic reaction, rare.

Treatment is not given in pregnancy or breastfeeding, in certain neuromuscular disorders, or where there is infection at the injection site. The risks that apply to you are discussed before treatment and again during consent. Results vary between people and no specific outcome is promised.

What affects the price?

The number of areas treated and the dose required, which depends on muscle strength. No prices are published on this site; any figure quoted before an assessment is indicative only. See the Medical Disclaimer.

Can it be combined with other treatments?

Frequently. Botulinum toxin addresses movement; fillers address volume and contour; skin treatments address quality and texture. They answer different problems and are often planned together.

If your concern is the shape of your nose rather than the lines around it, that is a surgical question — see rhinoplasty.

Frequently asked questions

How long does it last?

Commonly around three to four months for facial expression lines, after which movement gradually returns. Duration varies with the area treated, the dose, muscle strength and the individual, and it is an average rather than a promise.

When will I see the effect?

Movement usually begins to soften after three to seven days, with the full effect at about two weeks. A review appointment at two weeks is the point at which any adjustment is considered — not earlier.

Will my face look frozen?

That depends on dose and placement rather than on the product. A conservative dose softens movement while leaving expression; the target is discussed before treatment. If you want a subtle result, say so — it is a normal request and it changes the plan.

Which lines does it not treat?

Botulinum toxin works on lines made by muscle movement. Lines already etched into the skin at rest, volume loss and skin laxity are different problems and need different treatments — or, in some cases, surgery.

Is it safe?

It is one of the most widely studied aesthetic treatments, and systematic reviews of randomised trials have examined its effect and duration in upper facial lines. It still carries risks, including drooping of an eyelid or eyebrow, and it should be given by a physician who knows facial anatomy.

Can I have it if I am pregnant or breastfeeding?

No. Treatment is not given during pregnancy or breastfeeding. It is also avoided in people with certain neuromuscular disorders and in the presence of infection at the injection site.

What should I avoid immediately afterwards?

Usual advice is to stay upright for several hours, avoid rubbing or massaging the treated area, and postpone strenuous exercise, saunas and heavy alcohol until the next day. Your own instructions are given at the appointment.

Izmir · Bornova

Appointments and contact

You can reach the practice by phone or WhatsApp. Messages in Turkish, English, Bulgarian and Russian are all read by the surgeon.

Information given over messaging is general guidance only and does not create a doctor–patient relationship. See the Medical Disclaimer for details.

References

The information on this page is compiled from the sources below. All links were reachable when last checked.

  1. American Society of Plastic Surgeons. Botulinum toxin
  2. MedlinePlus (U.S. National Library of Medicine). Botox (botulinum toxin)
  3. Rahman E, Mosahebi A, Carruthers JDA, et al.. The efficacy and duration of onabotulinumtoxinA in improving upper facial expression lines with 64-unit dose optimization: a systematic review and meta-analysis. Aesthetic Surgery Journal 43(2):215-229 (2023). PMID: 36099476

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